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With the completion of several large clinical trials in nuclear medicine leading to significant breakthroughs for both dementia and cancer patients, this Online Course highlights PET imaging of proteinopathies for neurodegenerative disease, amyloid PET for dementia, FES-PET for breast cancer, as well as updates to treatments such as PRRT and Radium-223.Learning Outcomes and LecturesAfter completing this course, the learner should be able to:Explain the impact of PET imaging on the diagnosis and understanding of dementia.Discuss the benefits of novel imaging agents for oncology.Describe the landscape of therapeutic radiopharmaceuticals.Describe the role of nuclear medicine in theranostics.Speakers and LecturesBreakthroughs in PET for Neurodegenerative Diseases—P. KuoBreakthroughs in PET for Oncologic Imaging—K. ZukotynskiBreakthroughs in Radiotherapeutics and Theranostics—D. Yoo