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This CME Activity offers a practical review of genitourinary pathology combining basic to advanced techniques, pearls and pitfalls to pathologic diagnosis and case reviews.Target Audience This CME activity is intended and designed to educate pathologists.Educational Objectives At the completion of this CME teaching activity, you should be able to:Employ the diagnostic approach to assessing difficult prostate needle biopsy specimen.Explain the nomenclature and diagnostic approach to flat and papillary lesions of the urinary bladder.Describe the newest classification of renal tumors.Use a pattern-based approach to diagnose renal tumors.Program The Critical Role of the Pathologist in the Management of Bladder CancerDavid J. Grignon, M.D., FRCP(C)Diagnostic Dilemmas in Urinary Bladder PathologyChristopher Przybycin, M.D.Diagnostic Pitfalls in Bladder PathologyCristina Magi-Galluzzi, M.D., Ph.D.Pitfalls and Pearls in Bladder Biopsy and TURBT SpecimensCristina Magi-Galluzzi, M.D., Ph.D.Mimickers of Bladder NeoplasiaJonathan I. Epstein, M.D.The 2016 WHO Classification of Kidney Tumors: New Entities and Diagnostic ChallengesDavid J. Grignon, M.D., FRCP(C)Hereditary Kidney Tumors: Recognition and ClassificationChristopher Przybycin, M.D.Common Differential Diagnoses in Kidney and Testis LesionsJonathan I. Epstein, M.D.Classification of Testicular Germ Cell Tumors: How to Recognize What Matters and Avoid PitfallsChristopher Przybycin, M.D.Common Renal Cell Neoplasms and Their Differential DiagnosisCristina Magi-Galluzzi, M.D., Ph.D.Diagnosis, Staging, and Grading of Urothelial CarcinomaJonathan I. Epstein, M.D.Diagnosis and Reporting of Limited Adenocarcinoma on Needle Biopsy of the ProstateJonathan I. Epstein, M.D.Helpful Tips for Resolving Differential Diagnostic Consideration on Prostate BiopsyCristina Magi-Galluzzi, M.D., Ph.D.A Contemporary Approach to Prostate Adenocarcinoma, Including Poor Prognostic FactorsMichelle S. Hirsch, M.D., Ph.D.Diagnostic Approach to Difficult Prostate Needle BiopsiesMing Zhou, M.D.Reporting of Prostate Cancer in Needle Biopsy Specimens: Gleason Grading and MoreDavid J. Grignon, M.D., FRCP(C)Diagnostic Challenges in Prostate Needle BiopsiesCristina Magi-Galluzzi, M.D., Ph.D.Prostate Cancer Evolution: What the Pathologist Needs to KnowCristina Magi-Galluzzi, M.D., Ph.D.Prostate Carcinoma: Morphologic Subtypes and Areas of Diagnostic DifficultyCristina Magi-Galluzzi, M.D., Ph.D.Pattern Based Approach to Diagnosis and Classification of Renal TumorsMing Zhou, M.D.Renal Tumors with Eosinophilic Cytoplasm: A Practical ApproachCristina Magi-Galluzzi, M.D., Ph.D.A Diagnostic Approach to the many Subtypes of Renal Cell CarcinomaMichelle S. Hirsch, M.D., Ph.D.Diagnostic Approach to Flat and Papillary Urothelial LesionMing Zhou, M.D.Urothelial Carcinoma, Conventional versus Variant MorphologyMichelle S. Hirsch, M.D., Ph.D.Medicolegal Issues of Pathologists: General Aspects and Specific Cases Relating to Genitourinary PathologyJonathan I. Epstein, M.D.CME Release Date 4/01/2022CME Expiration Date 3/31/2025