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By Kenji Hashimoto, Mario MantoThis book discusses new candidates for rapid-acting antidepressants, such as (R)-ketamine, (2R,6R)-hydroxynorketamine, scopolamine, mGluR2/3 antagonists and AMPA receptor agonists. There are serious limitations to currently available antidepressants, such as delayed onset and low rates of efficacy. The discovery that a single dose of ketamine, an NMDAR antagonist, can produce rapid antidepressant effects that are sustained has led to new research in this area. In this volume, a variety of novel pharmaceutical treatments are examined. This volume would be useful to both researchers and clinicians who work in the field of pharmacology, specifically CNS drug treatments. Product DetailsPublisher : Springer; 1st ed. 2021 edition (October 23, 2021)Language : EnglishHardcover : 156 pagesISBN-10 : 3030797899ISBN-13 : 978-3030797898ISBN-13 : 9783030797898eText ISBN: 9783030797904