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By Damir Janigro, Astrid Nehlig, Nicola MarchiThis book provides comprehensive information, both for clinicians and scientists, on the basic mechanisms, clinical features, and therapeutic approaches to epilepsy as an inflammatory disease. Inflammation has been for many years considered as an etiologic player (and a therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure disorders. Many accepted therapies for non-inflammatory epilepsies act in part as an inflammatory drug. The CNS actively responds to acute immune challenges by altering body temperature, stimulating the HPA axis, as well as up- and down-regulating specific sympathetic pathways.Product DetailsPublisher : Springer; 1st ed. 2021 edition (May 19, 2021)Language : EnglishHardcover : 245 pagesISBN-10 : 3030674029ISBN-13 : 978-3030674021ISBN-13 : 9783030674021eText ISBN: 9783030674038
