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byWerner SchmidtWerner SchmidtAn illuminating summary of our current understanding of the interactive role of dopamine and glutamate in psychiatric diseases and the therapeutic strategies and possibilities for future treatment. Among the new ideas presented are hypotheses on the role of dopamine and glutamate in aggression, the glutamate system in anxiety disorders, glutamate and neurodegeneration, and on the origin and progression of Parkinson's disease. Additional chapters offer novel insights into a variety of psychiatric diseases, including ADHD, stress, aggression, addiction, schizophrenia, depression, social phobias, dementias, bulimia, and neurodegenerative diseases like Parkinson's and Alzheimer's diseases. Each chapter summarizes the prevalence and symptoms of the disease and explains the involvement of dopamine and/or glutamate systems using the newer molecular approaches such as transgenic knockout or knockin mice and recent brain imaging techniques.AdvertisingProduct DetailsISBN-13:9781588293251Publisher:Springer-Verlag New York, LLCPublication date:03/18/2005Edition description:2005Pages:600Product dimensions:7.01(w) x 10.00(h) x 0.05(d)Related SubjectsNeurologyNeuropsychology & NeuropsychiatryNeurosciencePharmacologyTable of ContentsPart I. DopamineDopamine ReceptorsKim A. NeveDopamine Receptor Alternative SplicingNeil M. Richtand, Laurel M. Pritchard, and Lique M. CoolenPart II. GlutamateGlutamatergic Pathways: Their Relevance for Psychiatric DiseasesYoland SmithGlutamate Receptors: IonotropicDaniel T. Monaghan, Julia C. A. More, Bihua Feng, and David E. JaneMetabotropic Glutamate ReceptorsKrystyna OssowskaPart III. SchizophreniaDopamine and SchizophreniaBart A. EllenbroekGlutamate and Schizophrenia and the N-Methyl-d-Aspartate Receptor Hypofunction HypothesisStefan Bleich and Johannes KornhuberRole of Glycine in SchizophreniaBeate D. KretschmerPart IV. DepressionDopamine and DepressionPhil SkolnickGlutamate and DepressionJoaquín Del Río and Diana FrechillaPart V. Stress and AggressionDopamine, Glutamate, and AggressionKlaus A. Miczek and Eric W. FishPart VI. AnxietyGlutamatergic Systems and AnxietyDavid N. StephensPart VII. Attention Deficit Hyperactivity DisorderDopamine and Glutamate in Attention Deficit Hyperactivity DisorderJames M. Swanson, Nora D. Volkow, Jeffrey Newcorn, B. J. Casey, Robert Moyzis, David K. Grandy, and Michael I. PosnerPart VIII. AddictionDopamine-Glutamate Interactions in Reward-Related Incentive LearningRichard J. Beninger and Todor V. GerdjikovSensitization and Relapse: Dopamine-Glutamate InteractionsDavid A. Baker and Peter W. KalivasGlutamatergic Neurotransmission in SensitizationThomas M. TzschentkeGlutamatergic Mechanisms of Drug Relapse: Withdrawal and Conditioning FactorsAnton Y. Bespalov and Robert L. BalsterPart IX. NeurodegenerationDopamine and NeurodegenerationGabriele Gille and Peter RiedererGlutamate and NeurodegenerationAntonello Novelli, Marcos Pérez-Basterrechea, and Maria Teresa Fernández-SánchezPart X. Parkinson's DiseasePresymptomatic and Symptomatic Stages of Intracerebral Inclusion Body Pathology in Idiopathic Parkinson's DiseaseHeiko Braak and Kelly Del TrediciDopamine and Glutamate in Parkinson's Disease: Biochemistry, Clinical Aspects, and TreatmentHeinz Reichmann, Bernd Janetzky, and Peter RiedererDopamine and Glutamate in Motor and Cognitive Symptoms of Parkinson's DiseaseWerner J. SchmidtPart XI. Huntington's DiseaseDopamine and Glutamate in Huntington's DiseaseCarlos Cepeda, Marjorie A. Ariano, and Michael S. LevinePart XII. DementiasDopaminergic and Glutamatergic Systems in Alzheimer's DiseasePaul T. FrancisIndexProduct DetailsISBN-13:9781588293251Publisher:Springer-Verlag New York, LLCPublication date:03/18/2005Edition description:2005Pages:600Product dimensions:7.01(w) x 10.00(h) x 0.05(d)
