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by Venkatramanujan Srinivasan (Editor), Gabriella Gobbi (Editor), Samuel D. Shillcutt (Editor), Sibel Suzen (Editor) There is growing interest in the field of melatonin research regarding its neurobiological mechanisms as well as its repercussions in clinical practice. Melatonin: Therapeutic Value and Neuroprotection explores melatonin’s neuroprotective effects and discusses the therapeutic potential of melatonin and melatonin agonists in treating neurodegenerative diseases and other ailments. Topics include:The basic aspects of melatonin’s physiology, including its production, bioavailability, and metabolismThe functional importance of melatonin receptors and their role in mediating the therapeutic effectiveness of melatonin in cancerMelatonin’s effect on the regulation of blood pressure, sleep, and circadian rhythmsThe cardioprotective role of melatoninThe neuroprotective role in glaucoma, Alzheimer’s disease, Parkinson’s disease, and neurodegenerative diseasesUse as a therapeutic agent for treating epilepsy and degenerative discsTreatment for obesity, diabetes mellitus, and other metabolic disordersProtective role in peri-natal hypoxic-ischemiaThe contributors also examine the discovery of a number of melatonergic agonists, their potential role as antioxidants, and their therapeutic applications in treating glaucoma, Parkinson’s disease, Alzheimer’s disease, primary insomnia, and psychiatric disorders. Opening new vistas in our understanding of etiology, pharmacotherapy, and treatment, the book is a significant milestone in our knowledge about advances in melatonin’s physiology and its therapeutic application in a number of disorders.Product DetailsISBN-13: 9781482220094Publisher: Taylor & FrancisPublication date: 10/28/2014Pages: 573
