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###-Book Description Begin-###
by David Bensimon (Author), Vincent Croquette (Author), Jean-Francois Allemand (Author), Xavier Michalet (Author), Terence Strick (Author)
This book provides the basis for understanding the elastic properties of nucleic acids (DNA, RNA), the methods used to manipulate them (e.g. optical, magnetic and acoustic tweezers and traps), and how to observe their interactions with proteins (e.g. fluorescence microscopy, FCS, FRET, etc.). It then exemplifies the use of these various methods in the study of three families of DNA enzymes: polymerases, helicases and topoisomerases. The book aims not to be exhaustive, but rather to stimulate the imagination of readers in the application of these single molecule approaches to the study of DNA/RNA and their interactions.
Series: Oxford Graduate Texts
Hardcover: 224 pages
Publisher: Oxford University Press (February 6, 2019)
Language: English
ISBN-10: 0198530927
ISBN-13: 978-0198530923