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###-Book Description Begin-###
by John C. Lucchesi (Author)
Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence. These changes, consisting principally of DNA methylation, histone modifications, and non-coding RNAs, maintain or modulate the initial impact of regulatory factors that recognize and associate with particular genomic sequences. Epigenetic modifications are manifest in all aspects of normal cellular differentiation and function, but they can also have damaging effects that result in pathologies such as cancer. Research is continuously uncovering the role of epigenetics in a variety of human disorders, providing new avenues for therapeutic interventions and advances in regenerative medicine.
Paperback: 304 pages
Publisher: Oxford University Press (March 9, 2019)
Language: English
ISBN-10: 0198831218
ISBN-13: 978-0198831211
